Comments on: Alzheimer’s Drug to Treat Binge Eating Disorder /2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/ Health and Science Blog Covering Brain Topics Sat, 29 Dec 2018 04:00:22 +0000 hourly 1 https://wordpress.org/?v=5.0.3 By: TonyV /2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-368444 Thu, 04 Dec 2008 11:50:32 +0000 /?p=1790#comment-368444 I’m leery of any drug that promises to fix an illness that has been around for centuries. It seems to me that these drugs never pan out. What has finally worked for me is joining a 12 step program to fight my disease from the emotional/spiritual angle.

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By: The Neurocritic /2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-356670 Wed, 19 Nov 2008 21:01:52 +0000 /?p=1790#comment-356670 “There was no significant change in BMI, body weight, depression, or anxiety. ”

Doesn’t seem like it was subjectively helpful to the patients, then.

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By: Tiptoe /2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-353911 Mon, 17 Nov 2008 06:48:25 +0000 /?p=1790#comment-353911 Interesting study, though definitely needs to be on a larger scale. My feeling why memantine works is due to where the drug targets in the brain. Though the Alzheimer’s and BED are entirely different, it looks like memantine can help by blocking the NMDA glutamate receptors. With BED, this might be helpful in controlling the hormone leptin signaling.

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By: Neuroskeptic /2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-353286 Sun, 16 Nov 2008 20:19:51 +0000 /?p=1790#comment-353286 Hmm – that’s interesting. I wonder how it works (if it does?) I’d have thought that any appetite suppressant would be effective in B.E.D – does memantine suppress appetite? It’s a D2 agonist, amongst other things, so it might do.

Also, I know that antidepressants reduce binge eating in bulemia, and memantine has been trialled as an antidepressant (although it doesn’t seem to work very well.)

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