Comments on: Depression – A Disease of the Heart

By: Cyndy

Cyndy — Sat, 19 Apr 2014 22:53:40 +0000

Thanks Isabel for your comment and for the link!

By: Exercise for Depression – A Gold Standard Therapy

Exercise for Depression – A Gold Standard Therapy — Sun, 19 May 2013 12:46:53 +0000

[…] Depression – A Disease of the Heart […]

By: Danny Rook

Danny Rook — Tue, 06 Mar 2012 11:52:20 +0000

Appologies for spelling, typing on my ipad in bed while im supposed to be studying lol

By: Danny Rook

Danny Rook — Tue, 06 Mar 2012 11:51:24 +0000

I am an ex-police officer suffering from ptsd. I recently started having chest pains, was subjected to a stress test which showed i required further testing. I went through an angio gram which returned clear. I think the corellation between depression and cardio- fitness is well accepted considering the often coexistence of agorophobia with depression and this could well influence our heart. Whether there is a physiological response in the cardio-vascular system is another issue entirely.
I am in 3rd year of bachelor of psychology as I wanted to turn my conditon into a positive. I find the inter-relations between our brain and the rest of our body fascinating and look forward to being part of our ongoing discoveries of this amazing part of something that is inside all of us. That we are able to do so much but still know so little about our brain makes it exciting to read the latest research.

By: Richard Kensinger, MSW

Richard Kensinger, MSW — Sun, 04 Mar 2012 19:14:44 +0000

We also know that over time the tricyclic antidepressants & Lithium show some cardiotoxicity. As well stated by the previous author’s comment, this link of MD & cardiac dysfunction is not robustly established.

Rich

By: Isabel (retired RN)

Isabel (retired RN) — Sun, 04 Mar 2012 16:05:31 +0000

Correlation is not causation — a logical imperative which tends to get overlooked when assessing scientific studies.

Delayed recovery may be due to autonomic dysfunction, HPA (hypothalamic-pituitary-adrenal) axis disruption, mitochondrial impairment, or a combination of these (for instance, HPA axis disruption may be a sequela of autonomic dysregulation; mitochondrial damage tends to show up with fatigue pathology.)

As those with major depression know, diet and exercise simply don’t have the same effect as they did when they weren’t depressed. This metabolic shift indicates some degree of autonomic involvement and also supports a thesis recently reported in ScienceDaily, that depression may stem from a primitive immune response. Which would also help to explain its persistence in the genome.

Link: http://www.sciencedaily.com/releases/2012/03/120301103756.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fmind_brain+%28ScienceDaily%3A+Mind+%26+Brain+News%29